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CBD & Epilepsy: What we know so far

Epilepsy, one of the most common nervous system disorders affecting people of all ages, is a neurological condition characterized by recurrent seizures. Treatment for epilepsy includes anti-seizure medications and diet therapy. Surgery may be an alternative treatment, especially when medications or diet fail to control seizures, or if drug side effects are too difficult for a patient to tolerate.🧠

Currently Epidiolex, a pharmaceutical formulation of CBD is approved by the FDA to treat three types of rare seizure disorders;
1️⃣ Dravet syndrome
2️⃣ Lennox-Gastaut syndrome
3️⃣ Tuberous sclerosis complex
but is not approved for the many other types of epilepsy.

As a result, patients with other forms of epilepsy often seek alternative forms of CBD, including those evaluated in the new study. For their evaluation, the researchers analyzed data gathered between April 2016 and July 2020 from 418 participants ✍🏼


Participants completed a web-based survey that included questions regarding quality of life, anxiety and depression, and sleep. Compared with the control group, artisanal CBD users reported
👇🏼 lower epilepsy medication-related adverse effects (-13%)
👆🏼 had greater psychological health satisfaction (+ 21%)
👇🏼 lower anxiety (-19%)
👇🏼 lower depression (-17%).

Both adult and children CBD users reported better quality sleep, compared with their peers in the control groups 😴

Importantly, participants also were asked about possible adverse effects related to their CBD use. Among the 280 users 79% did not report any adverse effects 👏🏼

Ryan Vandrey, Ph.D., professor of psychiatry and behavioural sciences at the Johns Hopkins University School of Medicine said, “In our study, we saw clinically significant improvements in anxiety, depression and sleep when patients with epilepsy initiated therapeutic use of artisanal CBD products.” He also added further research is needed to understand how these findings can best be applied to helping people with epilepsy. In the interim, he says, patients should consult with their physician before trying CBD products. 💚🌿

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